Application of mesangial thyroid resection in papillary thyroid carcinoma with central lymph node dissection and its influence on postoperative recurrence

Abstract

Objective To explore the application of mesangial thyroid resection in papillary thyroid carcinoma(PTC) with central lymph node dissection, and its influence on postoperative recurrence. Methods 76 cases with PTC were divided into two groups according to random number table, each group in 38cases.The control group was given primary lesions radical prostatectomy and routine central lymph node dissection, the treatment group was given primary lesions radical prostatectomy and central lymph node dissection by thyroid mesangial resection.The parathyroid function, injury of recurrent laryngeal nerve and local recurrence were compared between the two groups. Results Compared with before surgery, the levels of serum PTH and blood calcium were significantly decreased at the 1st, 3rd day after surgery (all P 0.05). The levels of serum PTH and blood calcium at the 1st, 3rd, 7th day after surgery between the two groups had no statistically significant differences(all P<0.05). The incidence rate of injury of recurrent laryngeal nerve in the treatment group was significantly lower than that in the control group (5.3% vs.21.1%, χ2=4.15, P<0.05). The secondary surgery rate and local recurrence within 2 years in the treatment group were significantly lower than those in the control group(0% vs.15.8%, 2.6% vs.18.4%, χ2=6.51, 4.69, all P<0.05). Conclusion Primary lesions radical prostatectomy and central lymph node dissection by thyroid mesangial resection can be used as the routine operation for PTC, which can effectively produce complete dissection, reduce injury of recurrent laryngeal nerve and local recurrence. Key words: Thyroid neoplasms; Neck dissection; Recurrence