Application of Hyperthermia for Cancer Treatment: Various Techniques and Recent Advancement

Abstract

Cancer is a disease characterized by uncontrollable cell division in a specific area of the body. It is a leading cause of death, and its prevalence is increasing. There are numerous techniques and protocols employed, including as chemotherapy, radiography, surgical tumor removal, etc. However, these procedures have a number of negative side effects that cause excruciating pain and intense anxiety in the patients. It has been increasingly difficult to find new cancer-fighting strategies during the past few decades. One of the best cancer treatment choices is hyperthermia, an ancient form of therapy that offers fresh hope when paired with engineering methods. This study examines the crucial data for the coupling with hyperthermia of various engineering techniques, which is carefully organized according to the techniques used, such as hyperthermic perfusion, frequency enhancers, ultrasonic hyperthermia, external radio-frequency devices, microwave hyperthermia, using a catheter, heat the target area before injecting superparamagnetic and magnetic nanoparticles.