Abstract
Differential tnermal analysis (DTA) was used to identify stearic acid as the inactivating component in an unstable formulation containing sodium dicloxacillin and several excipients. Analyses were also performed on mixtures of stearic acid with potassium penicillin G, with sodium oxacillin monohydrate, and with ampicillin trihydrate. The resulting thermograms indicated the former two mixtures to be incompatible and the latter mixture to be compatible. The results as obtained by DTA gave excellent correlations with those obtained by an 8-week, 50° stability test.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
