Application of dezocine in medical thoracoscopy

Abstract

Objective To observe the analgesic and sedative effects of dezocine injection on the medical thoracoscopy check-up. Methods 98 cases of patients with unexplained pleural effusion were randomly divided into sedation group(dezocine group, 49 cases) and anesthesia group(local anesthesia by lidocaine, 49 cases) by adopting digital expression method.Sedation group was intravenously injected with 5mg dezocine before the operation, and another 5mg dezocine was mixed with 100mL of 0.9% sodium chloride for intravenous drip, with 10mL of 2% lidocaine for local anesthesia during the operation; anesthesia group was only administered with 10mL of 2% lidocaine for local anesthesia.Verbal rating scales(VRS) results and visual analogue scales(VAS) results of the two group patients, as well as their hemodynamics and pleural reaction were recorded. Results The VAS scores of the sedation group and anesthesia group were (4.3±2.2)points and (2.1±1.9)points, respectively, VRS scores were (3.5±1.1)points and (1.4±1.1)points, there were statistically significant differences(t=0.415, P=0.019 and t=0.293, P=0.006, respectively). The two groups had basically similar operation duration, but the sedation group had more stable hemodynamic indexes such as maximum heart rate, systolic pressure, diastolic pressure and pleural reaction, including cough, dizziness, chest tightness, sweating, etc. Conclusion Dezocine injection can be used in medical thoracoscopy check-up and treatment, with significant analgesic effect and less adverse reaction, effectively alleviating the discomfort of thoracoscopy check-up, and improving patients′ compliance and comfort, so as to enhance the success rate of thoracoscopy check-up. Key words: Thoracoscopy; Dezocine