Application of COOK® cervical ripening balloon combined with artificial rupture of membranes and oxytocin in labor induction for full-term pregnancy

Abstract

Objective: The use of COOK[Formula: see text] balloon in the process of induction of labor is gradually promoted. This study was conducted to investigate the safety and efficacy of COOK[Formula: see text] double balloon in promoting the maturity of uterine neck, and whether COOK[Formula: see text] double balloon can improve the success rate of induced labor. Methods: A total of 343 pregnant women with full-term pregnancy in Shanghai Putuo Maternity & Infant Health Hospital from January 1st to September 30th of 2016 were enrolled. Of all the pregnant women, 166 had labor induction, which included the use of a COOK[Formula: see text] balloon, the implementation of artificial rupture of membranes (AROM) and oxytocin intravenous (IV) drip (COOK[Formula: see text] group). The other 177 pregnant women with spontaneous rupture of membranes (SROM) and mature cervix only were administrated with oxytocin IV drip to promote regular uterus contraction (oxytocin group). Maternal adverse reactions, mode of delivery and delivery outcomes of two groups were subsequently compared between the two groups. Results: There were significant differences of maternal age ([Formula: see text] versus [Formula: see text] years, [Formula: see text]), gestational age ([Formula: see text] versus [Formula: see text] years, [Formula: see text]) and birth weight ([Formula: see text] versus [Formula: see text][Formula: see text]g, [Formula: see text]) between the COOK[Formula: see text] group and the oxytocin group. There were no significant differences in terms of gravidity, parity, mode of delivery, analgesia, 1 min and 5 min Apgar score, labor time, postpartum hemorrhage, and adverse events. Conclusion: Use of a COOK[Formula: see text] balloon may help in full-term pregnancy for women with immature cervix and to obtain the same pregnancy results as those with mature cervix, without extra occurrence of adverse events.