Abstract
Objective To explore the significance and application of the angle between the canthomeatal line (CML) and the anterior commissure-posterior commissure (AC-PC) line in the sagittal plane projection in stereotactic neurosurgery. Methods Quantitative MRI was performed in a crosssectional analysis of 120 normal volunteers from south China; the angle between the canthomeatal line and the AC-PC line in the sagittal plane projection, the length of the intercommissure line, and the vertical distance from external auditory canal midpoint to the AC-PC plane were measured and matched for age and gender. Results The average angle between the CML and the AC-PC line in the sagittal plane projection of all South China adult brains is (12.03± 1.11)° , which is (12.17± 1.06)° in male and (11.89±1.14)° in female. The average length of AC-PC line is (23.74±0.95)° mm, which is (24.35±0.64)° mm in male and (23.14±0.95)° mm in female. The average length of the vertical distance from external auditory canal midpoint to the AC-PC plane of all is (48.69±4.03) mm, which is (49.57±3.10) mm in male and (47.82±4.61) mm in female. Clinical validation showed that the deviation angle to the actual AC-PC plane was (1.56±0.63) . Conclusion The angle formed by CML and the AC-PC plane is stable in adults of different gender and ages; taking CML as a baseline, the surface projection of AC-PC line can be drew with the angle and the vertical distance, and then, the AC-PC plane by adjusting the directional headstock can be obtained with high accuracy, repeatability and maneuverability; therefore, these datacan be used as a valuable reference of adult brain structure of Han nationality in South China. Key words: Functional stereotaxis; Anterior commissure; Posterior commissure; Canthomeatal line; Nuclear magnetic resonance
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