Abstract
The article outlines the diagnostic criteria for chronic constipation, provides epidemiological data on the prevalence of the condition among the population, and specifies the main types of laxatives. The author presents own findings on the possibility of combined treatment with trimebutine and a combination microenema laxative for patients with “lazy bowel” syndrome which develops against a background of long-term use of irritant laxatives. The author concludes on the good tolerability and positive efficacy of the combination therapy involving drugs which normalize intestinal motility and micro-enemas containing sodium citrate, sodium lauryl sulfoacetate and sorbitol solution in such patients.
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