Abstract
Melanosis coli is a rare condition characterized by dark discoloration of the colonic mucosa. It is associated with long term use of anthraquinone-containing laxatives. It may be mistaken for other colonic diseases including ischaemic colitis. We present a middle-aged female with history of chronic constipation and longterm use of laxatives. Colonoscopy identified dark brown – black discoloration of the colonic mucosa which was suggestive of melanosis coli and confirmed by histology. The significance lies in the rarity of melanosis coli and the importance of avoiding a misdiagnosis. Dietary measures should be instituted in individuals with chronic constipation in order to avoid prolonged laxative use and possible development of melanosis coli.
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