Application and nursing of high replacement rate continuous renal replacement therapy (CRRT) in severe acute pancreatitis (SAP) complicated by acute respiratory distress syndrome ( ARDS )

Abstract

Objective To study the application and nursing of high replacement rate continuous renal replacement therapy (CRRT) in severe acute pancreatitis ( SAP), complicated by acute respiratory distress syndrome ( ARDS) .Methods Twenty four cases of severe acute pancreatitis ( SAP) concurrent ARDS patients were treated with high replacement rate CRRT treatment by ventilator support.Dynamically observing life signs,oxygenation index,APACHE - Ⅱ score,positive end expiratory pressure ( PEEP) level were compared before and after treatment.Results Fifteen cases of patients were treated successfully on high replacement ratio CRRT therapy.the level of A PACHE - II score,body temperature,breathing,heart rate,mean arterial pressure,and positive end expiratory pressure ( PEEP) were significantly decreased (P < 0.05).oxygenation index was increased significantly (P < 0.05) .Conclusions Early application of high replacement rate CRRT treatment,can alleviate clinical symptoms,improve disease,improve the success rate of treatment. Moreover it plays an important role to improve therapeutic effect of severe acute pancreatitis concurrent acute respiratory distress syndrome by clirucal closely monitoring and scientificly nursing. Key words: High replacement rate CRRT; Severe acute pancreatitis (SAP); Acute respiratory distress syndrome (ARDS); Nursing