Abstract
Objectives: Familial hypercholesterolemia (FH) is a common autosomal dominant disorder of lipid metabolism. The high levels of plasma cholesterol since birth confer an increased risk of coronary heart disease. Clinical diagnosis of FH is usually done using a set of criteria (MEDPED or Simon Broome Registry (SBR)), however only SBR presents criteria for children. The present work aims to identify useful biomarkers for clinical criteria improvement in clinical settings.
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