Apnea in Term and Late Preterm Neonates Born to Coronavirus Infected Mothers

Jaimin Patel,Renjithkumar Thekkeveedu,Jagdish Desai,Tasha Coleman,Nilesh Dankhara,Alisia Hankins,Mobolaji Famuyide

doi:10.51362/neonatology.today/20201215121219

Jaimin Patel, Renjithkumar Thekkeveedu + Show 5 more

Open Access

https://doi.org/10.51362/neonatology.today/20201215121219

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Abstract

We report three otherwise healthy neonates born to Coronavirus Disease-19 (COVID-19) positive mothers who developed apnea during birth admission but tested negative for COVID-19. We postulate that the apnea may be due to transplacental transmission of infammatory cytokines. We strongly advise against early discharge in babies born to mothers with active COVID-19 infection.

Highlights

COVID-19 syndrome in pregnancy is often reported as mild to moderate in severity. [1, 2] The clinical presentation of COVID-19 syndrome in pregnancy is similar to that seen in non-pregnant adults
“In our case series, we report a series of term and a late preterm neonate born to COVID-19 infected mothers who presented with apnea, bradycardia, and desaturation episodes during birth hospital admission.”
We report a series of term and a late preterm neonate born to COVID-19 infected mothers who presented with apnea, bradycardia, and desaturation episodes during birth hospital admission

Summary

Introduction

COVID-19 syndrome in pregnancy is often reported as mild to moderate in severity. [1, 2] The clinical presentation of COVID-19 syndrome in pregnancy is similar to that seen in non-pregnant adults. We report a series of term and a late preterm neonate born to COVID-19 infected mothers who presented with apnea, bradycardia, and desaturation episodes during birth hospital admission. Neonate 1 was born to a 22-year-old Gravida 3, Term 2, Preterm 1, Abortion 0, Living 3 (G3P2103) mother at 40 weeks of gestation via C-Section and presented with apnea at 26 hours of age. Neonate 2 was born to a 17-year-old G2P0010 mother at 35 weeks 6 days of gestation via C-Section and presented with apnea at 19 hours of age. Neonate 3 was born to a 28-year-old G2P2002 mother at 40 weeks of gestation via vaginal delivery and presented with apnea at 65 hours of age. We present three neonates born at term/late preterm gestational age, who tested negative for Coronavirus via real-time polymerase chain reaction (RT-PCR), yet presented with apnea-

No CRP available Not done

Findings

Apnea and emesis