Abstract
vitro m e a s u r e m e n t o f 22Na influx into red blood cells will establish the diagnosis o f Liddle syndrome pr ior to therapy in pat ients who have hyper tens ion and hypokalemia wi thou t demons t r ab l e renal or adrenal pathology. The demons t r a t i on o f increased t ranspor t o f sodium into erythrocytes and the absence of mineralocor t icoid excess suppor t the view that Liddle syndrome is due to a general ized m e m b r a n e abnormal i ty .
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