Abstract

Aortic dissection (AD) is a rare disease that may result in a fatal outcome. Uremic patients are often associated with factors susceptible to AD. We herein report two cases of AD occurring in maintenance haemodialysis patients. The two male Chinese had history of smoking and poor uncontrolled hypertension for many years. One patient died of the aortic wall rupture with conservative treatment. The other patient had a history of myocardial infarction and long-term administration of anti-platelet drugs. The patient survives after prompt stenting and continuous maintenance haemodialysis. It is important to improve our understanding about aortic dissection (AD) in haemodialysis patients because of the high mortality and morbidity. Once a patient on maintenance haemodialysis is diagnosed with AD, surgery or endovascular graft exclusion should be considered according to the actual situation of individual patients, and the mode of dialysis should be converted in conservation treatment patients.

Highlights

  • Aortic dissection (AD) refers to the intimal tear due to damage of the normal structure of the aortic wall from various reasons

  • A 50-year-old Chinese male patient who had been on maintenance haemodialysis for a year at twice-a-week regular intervals came to the hospital because of sudden onset of persistent severe chest pain, when BP was 176/90 mmHg and HR was 88 bpm

  • Patients on maintenance haemodialysis are often associated with hypertension, lipid and calcium phosphorus metabolic disorders, arteriosclerosis, and hemodynamic change, all of which may contribute to the occurrence of AD [3,4,5]

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Summary

Introduction

Aortic dissection (AD) refers to the intimal tear due to damage of the normal structure of the aortic wall from various reasons. This article reports two cases of AD occurring in patients on maintenance haemodialysis between 2000 and 2013 in the department of haemodialysis of the hospital. A 50-year-old Chinese male patient who had been on maintenance haemodialysis for a year at twice-a-week regular intervals came to the hospital because of sudden onset of persistent severe chest pain, when BP was 176/90 mmHg and HR was 88 bpm.

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