Anxiety, depression and global distress among African American young adults with uncontrolled asthma

Abstract

Background Anxiety and depression are mental health disorders that are often comorbid with asthma. Urban African American young adults with asthma often experience increased risk of anxiety and depression. Objective To explore relationships between symptoms of psychological distress and asthma-related anxiety with asthma outcomes among urban African American young adults with poorly controlled persistent asthma. Methods A secondary analysis of baseline data from a larger study of 141 African American young adults with uncontrolled persistent asthma was examined. Participants completed the Brief Symptom Inventory (BSI-18), Youth Asthma-related Anxiety Scale, Asthma Control Test (ACT), a daily diary to assess asthma symptoms; and number of asthma attacks. Spirometry assessed airway obstruction. Generalized linear models tested associations. Results In multivariable models testing, higher somatization scores were significantly associated with lower ACT scores (adjusted β = −0.49; 95% CI = −0.69, −0.28; p < 0.01), and higher symptoms (adjusted β = 0.39; 95% CI = 0.14, 0.65; p < 0.01). After adding asthma-related anxiety to the model, the somatization subscale and asthma-related anxiety were significantly associated with ACT scores (adjusted β = −0.36; 95% CI = −0.57, −0.15; p < 0.01), (adjusted β = −0.32; 95% CI = −0.50, −0.14; p < 0.01), respectively. Asthma-related anxiety was also significantly associated with asthma attacks (adjusted β = 0.24; 95% CI = 0.05, 0.43; p < 0.05). Conclusion This study suggests, asthma-related anxiety may differ from general anxiety and be related to poorly controlled asthma among African American young adults.