Abstract
Due to the high prevalence of viral infections having no specific treatment and the constant emergence of resistant viral strains, searching for effective antiviral compounds is crucial. The present study explores in vitro the antiviral activity of ethanolic extract from aerial parts of. The aim of the current study was to evaluate antiviral activity of ethanolic extract from herbaceous plant. The crude aqueous ethanolic extract from aerial parts of. The results show that the extract has the lowest toxicity on the MDBK cell line and similar cytotoxicity in Hep-2, whereas in the MDCK cells it has more than twice the highest toxicity. Testing the antiviral activity of. The crude extract from aerial parts of the medicinal plant.
Highlights
Due to the high prevalence of viral infections having no specific treatment and the constant emergence of resistant viral strains, searching for effective antiviral compounds is crucial
The results show that the extract has the lowest toxicity on the Madin-Darbey bovine kidney (MDBK) cell line and similar cytotoxicity in Hep-2, whereas in the Madin-Darby canine kidney (MDCK) cells it has more than twice the highest toxicity
Testing the antiviral activity of Tanacetum vulgare L. extract revealed a slight inhibition of replication of HSV-1 with a selective index of 7.07 and IAV/H3N2 (SI = 3.69) but no specific antiviral effect against CVB1 replication was found
Summary
Due to the high prevalence of viral infections having no specific treatment and the constant emergence of resistant viral strains, searching for effective antiviral compounds is crucial. The herb should not be used for self-medication and should only be used as prescribed and under medical supervision Many biological activities, such as antibacterial, antiviral, antifungal, anti-inflammatory, immunomodulatory, antihypertensive, antioxidant, antitumor and many others have been described for extracts and active compounds isolated from Tanacetum vulgare.[4,5,6,7,8,9,10] The antioxidant activity of extracts from various representatives of genus Tanacetum has been established using different techniques. It is supportive to the traditional medicinal application of the plant for conditions such as wound healing, rheumatic arthritis and other inflammatory conditions.[11,12] Currently, some pharmacopoeias have described the use of tansy in anti-inflammatory drugs[13] and in drugs used for treatment of colds and fever[14]
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