Abstract
The effect of water soluble extract of Sanicula europaea L. leaves and two fractions separated from this extract through Sephadex gel filtration chromatography were tested on bacteriophage T2hr+ replication. The plant extract inhibited the adsorption and/or penetration of phage infection without any toxic effect on Escherichia coli B2 host bacteria. The heavy molecular weight fraction eluted first from the gel filtration column was found to be responsible for this inhibition.
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