Abstract

Zanthoxylum armatum is a well known food product used as antispasmodic in traditional medicine system. In the present research work, the phytochemical composition of the leaves, barks and fruits was carried out showing that all parts are good source of alkaloids, saponin, tannins and flavonoids. The ethanolic and n-hexane extracts were tested for their antispasmodic potential using rabbit ileum tissues. The ethanolic and n-hexane extract of the leaves (ZLE and ZLH), barks (ZBE and ZBH) and fruits (ZFE and ZFH), demonstrated a dose dependant antispasmodic effect. In most of the tested extracts, the action of ethanolic extract was found more pronounced than the other. The most significant antispasmodic effect was observed with fruit extracts. In conclusion, the current study strongly supports the folkloric uses of the plant as antispasmodic. Key words: Zanthoxylum armatum, rabbit ileum, phytochemical studies, folkloric, antispasmodic.

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