Abstract
Bryophyllum pinnatum (Lam.), Viscum album (L.) and Artocarpus altilis (Parkinson) are medicinal plants widely used based on their ethnomedicinal properties in the regulation of blood pressure. This study was designed to evaluate the antioxidant activities and compositional constituents of these plants. The antioxidant potentials were analyzed using DPPH and FRAP assays, while Folin-Ciocalteu method was employed in the determination of the total phenolic antioxidant contents. Compositional analyses of the leave extracts were determined using Gas Chromatograghy-Mass Spectrophotometer (GC-MS). The total phenolic contents in Bryophyllum pinnatum, Artocarpus altilis and Viscum album were revealed as; 659.50 ±0.02, 1667.50 ±0.03, 1232.00 ±0.02 mg GAE.100 g-1 respectively. Considering the antioxidant activities, Artocarpus altilis leaf extract showed inhibitory activity on DPPH with IC50 of 2.24 ±0.26 mg.mL-1, Bryophyllum pinnatum and Viscum album with IC50 values 3.63 ±0.07 and 4.65 ±0.06 mg.mL-1 respectively.The FRAP in mg.GAE-1 for Artocarpus altilis, Bryophyllum pinnatum and Viscum album revealed; 2505.20 ±0.04, 1561.80 ±0.01 and 1698.00 ±0.03 respectively. GC-MS identified some vital phenolic components and essential fatty acids in the plants. The findings therefore suggest that; the plants if properly utilized, it could serve as alternatives in regulating blood pressure.
Highlights
Occurrence of diseases have been increasing at a regular rate and claiming millions of lives in spite of the huge improvements in modern medicine all over the world
Bryophyllum pinnatum (Lam.), Viscum album (L.) and Artocarpus altilis (Parkinson) are medicinal plants widely used based on their ethnomedicinal properties in the regulation of blood pressure
The total phenolic content of the methanolic leave extracts are presented in Table 1 as 659.5, 1667.5 and 1232.0 mg GAE.g-1 dry extract for B. pinnatum, A. altilis and V. album respectively
Summary
Occurrence of diseases have been increasing at a regular rate and claiming millions of lives in spite of the huge improvements in modern medicine all over the world. Despite tremendous progress in human medicines, infectious diseases caused by bacteria, fungi, viruses and parasites are still a major threat to public health. Their impact is great in developing countries due to relative unavailability of medicines and the emergence of widespread drug resistance (Abubakar et al, 2010). Studying medicinal plants helps to understand plant toxicity and protect human and animals from natural poisons (Hosseinzadeh et al, 2015).Various herbal plants have been used to combat hypertension.Bryophylum pinnatum (B. pinnatum), Viscum album Altilis) are examples of the various medicinal plants basically used individually in ethno-medicine for the regulation of blood pressure and in the treatment of hypertension
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