Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes

Abstract

<p>Steppe peony (<em>Paeonia tenuifolia</em> L., Paeoniaceae) is a perennial, herbaceous plant species which has been widely known for its medicinal use. This study is aimed at the development of <em>P. tenuifolia </em>petal dry methanolic extract-loaded liposomes and the determination of their antioxidant activity. The liposomes were prepared with three different phospholipid mixtures by the proliposome method. The antioxidant potential of the liposomes was assessed by the 2,2′-azino-bis(3 ethylbenzothiazoline-6-sulfonic acid) (ABTS<sup>•+</sup>) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging methods. The ABTS radical scavenging activity ranged from 66.99 to 69.15%, whereas for the DPPH, the values varied from 85.12 to 90.11%. These results revealed promising antioxidant activities of <em>P. tenuifolia</em> petal extract-loaded liposomes with the potential to be used for the treatment of health disorders associated with oxidative stress, such as skin-related problems.</p>