Abstract

The use of medicinal plants for disease prevention, treatment and cure is an ancient practice used by humanity, and many plants species are used in bioprospecting research. In this context, its stands out Eugenia uniflora L., populary known as pitangueira and belongs to the Myrtaceae family, with a wide geographic distribution and native of Brazil. In view of the therapeutic qualities of the plant and the lack of the studies on its seeds, the present study had as objective to evaluate the phytochemical profile of the extracts of Eugenia uniflora L. seeds, from different solvents, as well as their antibacterial activity, antioxidant and its inhibitory effect of intestinal disaccharidases. Results showed a high content of phenolic compounds and total flavonoids, thus characterizing antioxidant activity, also highlighting the best bacteriostatic action for the Gram positive strain of Staphylococcus aureus in the ethanolic fraction. Regarding the disaccharidases, a strong inhibitory action was observed for all concentrations, evidencing a antihyperglycemic potential. The present research allowed to concluded that Eugenia uniflora L. seeds have promising biological activities for the industrial sector, but a more detailed investigation is needed regarding their bioactive compounds.

Highlights

  • Several plants have been used by humanity in all continents to control different diseases and pests, beyond representing an important source of biologically active natural products, many of which constitute a model for theBraz

  • In a study carried out by Mendonça et al (2016) with ethanolic extracts of leaves and stems of pitangueira, the results demonstrated antimicrobial activity against strains of E. coli, S. aureus and Pseudomonas sp

  • These results indicate that seeds employed in this work have antioxidant chemicals capable of capturing free radicals, aiming at the prevention of diseases resulting from oxidative stress

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Summary

Introduction

Several plants have been used by humanity in all continents to control different diseases and pests, beyond representing an important source of biologically active natural products, many of which constitute a model for theBraz. Several plants have been used by humanity in all continents to control different diseases and pests, beyond representing an important source of biologically active natural products, many of which constitute a model for the. Yunes and Cechinel (2014) emphasized the importance of ethnobotanical and ethnopharmacological studies on increasing the medicinal plants knowledge and encourage the sustainable use of the plants biodiversity. In this context the E. uniflora, popularly known as pitangueira, which was selected for study, it is already used in the popular medicine with therapeutic qualities. It is already known that essential oils extracted from those plants display antimicrobial and antioxidant properties (Dorman and Deans, 2000; Duarte, 2006; Andrade et al, 2007)

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