Abstract
Abstract Biopesticides offer a more sustainable solution to pest control than synthetic alternatives. Naturally plant products, called secondary metabolites include thousands of alkaloids, terpenoids, phenolics and minor secondary chemicals. Sophora flavescens Aiton (Leguminosae) is an ancient Chinese herb that grows wild in China. About two dozen alkaloids have been identified in Ku Shen, with matrine and oxymatrine being the major compounds. Ku Shen extracts have been formulated as pesticides either alone or in mixtures with conventional synthetic pesticides. In this study we have analyzed the probable cytotoxic and genotoxic effects of oxymatrine on plant test system for determining the safety of use as biopesticide. This alkaloid has reduced the mitotic index in Allium root meristem in higher concentrations but hasn’t show distinct genotoxic effects. In conclusion oxymatrine can be proposed as safe at this end point for using as biopesticide while the plant physiological system can ruled out certain e...
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