Antimicrobial susceptibility pattern of bacteria isolated from urinary tract infection in Federal Teaching Hospital Ido Ekiti

Oguntunnbi Damilola Esther Oguntunnbi Damilola Esther,Oyekale Oluwalana Timothy Oyekale Oluwalana Timothy,Ojo Bola Oluwatosin Ojo Bola Oluwatosin,Adegbile Samsudeen Adeniran Adegbile Samsudeen Adeniran

doi:10.53771/ijbpsa.2021.2.2.0092

Oguntunnbi Damilola Esther Oguntunnbi Damilola Esther, Oyekale Oluwalana Timothy Oyekale Oluwalana Timothy + Show 2 more

Open Access

https://doi.org/10.53771/ijbpsa.2021.2.2.0092

Copy DOI

Abstract

The problem of antibiotic resistance remains a major concern among the patients and health care provider. This study was carried out therefore to determine the antibiotics resistance susceptibility pattern bacteria with urinary tract infections among patients attending Federal Teaching Hospital Ido-Ekiti. A total of 200 patients suspected of having a UTI were recruited for the study. The urine samples were cultured on Cysteine Lactose Electrolyte Deficient Agar (CLED) and the colonies were identified using colonial morphology and biochemical test. Antibiotics susceptibility testing was carried out using Kirby-Bauer disk diffusion techniques. Out of 200 urine samples analysed 82 (41.0%) yielded significant bacteria growth belonging to 4 different genera with Escherichia coli having the highest isolation rate 42 (81.2%) followed by Pseudomonas aeruginosa 16 (19.5%), Staphylococcus aureus 14 (17.0%) and Klebsiella aerogenes 10 (12.1%). Female patients had the highest isolation rate of 48 (58.5%) compare to their male counterpart with 34 (41.5%) isolation rate. Age group 31-40yrs had the highest isolation, rate of 20 (24.4%). The antibiotic resistance pattern exhibited by all the bacteria ranged from 14.3% to 90.5%. Gentamicin exhibited the least resistance rate. However, antibiotics resistance is frightening; therefore, there is a need for antibiogram before prescription of antibiotics for the treatment of urinary tract infection.

Highlights

Urinary Tract Infection (UTI) is one of the most common infectious disease ranking next to upper respiratory tract infection and is the cause of morbidity and mortality in human both in the community and hospital settings [1, 2]
It showed that female subjects had highest isolation rate of bacteria compare to their male counterpart 34 (41.5%)
Urinary tract infection is a common health problem worldwide and the antibiotic resistance pattern associated bacteria varies from region to region

Summary

Introduction

UTI is one of the most common infectious disease ranking next to upper respiratory tract infection and is the cause of morbidity and mortality in human both in the community and hospital settings [1, 2]. Approximately 150 million people are diagnosed with UTIs resulting in USD 6 billion health care expenditures [3, 4]. UTI can be asymptomatic or symptomatic, characterized by a wide spectrum of symptoms ranging from mild irritative voiding to bacteremia, sepsis or even death. UTIs that occur in a normal genitourinary tract with no prior instrumentation are considered as “uncomplicated,” whereas “complicated” infections are diagnosed in genitourinary tracts that have structural or functional abnormalities, including instrumentation such as indwelling urethral catheters, and are frequently asymptomatic [7,8,9]. Other major symptoms may include: strong urge to urinate frequently, even immediately after the bladder is emptied (Urgency), painful burning sensation when urinating (Dysuria), discomfort, pressure, or bloating in the lower abdomen, pain in the pelvic area or back, cloudy or bloody urine (Haematuria), which may have a strong smell, urination during the night (Nocturia), frequent urination (Polyuria) [5, 6].

Methods

Results

Discussion

Conclusion