Abstract
New maleimide Monomers, homopolymers and copolymers containing azo, sulfonamide and thiazole groups were synthesized. The structures of newly synthesized compounds have been characterized on the basis of their spectroscopic data (FT-IR and 1H-NMR). Antimicrobial studies of synthesized compounds were performed using agar well diffusion method. All the compounds showed pronounced activity against bacterial strains in comparison to activity against fungal strains.The highest antibacterial potency was exhibited by the homopolymer HPSPMI against Escherichia coli, Klebsiella pneumoniae and Bacillus subtilis. The activity of HPSPMI against later two was more pronounced than the standard drug used. Only Selected compounds showed antifungal activity. Appreciable results were found against Aspergillus fumigates but not with Candida albicans. HPSPMI showed highest activity against Aspergillus fumigates. Surprisingly after homo and copolymerization, maximum compounds exhibited not only pronounced antibacterial activity but also antifungal activity.
Highlights
Antimicrobial polymer, known as polymeric biocides is a class of polymers with antimicrobial activity or the ability to inhibit the growth of microorganisms
All synthesized compounds showed excellent to moderate antimicrobial potency
The highest antibacterial and antifungal activity was exhibited by the homopolymer HPSPMI against Escherichia coli, Klebsiella pneumoniae and Bacillus subtilis and Aspergillus fumigates
Summary
Antimicrobial polymer, known as polymeric biocides is a class of polymers with antimicrobial activity or the ability to inhibit the growth of microorganisms. Significant advance in the past three decade have been made in the synthesis and application [1] of polymers to prevent microbial attack [2][3][4][5] and degradation for diverse end uses. This led to the discovery of a variety of new polymers with bioactive functional groups. To a solution of parent compound (from which monomer has to be synthesized) in appropriate quantity of DMF solvent.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
