Abstract
The silver nanoparticles (AgNPs) show high antimicrobial activity, confirmed by a number of researchers. Due to the widespread occurrence of microbial strains with multiple resistance to antibiotics, the possibilities for the diverse practical application of AgNPs have become the subject of research nowadays. They have numerous potential biomedical applications due to the antimicrobial activity even against polyresistant strains combined with low cytotoxicity. In many cases, this activity is enhanced when they are combined with antibiotics, plant extracts and other substances. However, serious irreversible adverse health effects have been identified. Elucidation of their exact mechanisms of action in the cells not only of microorganisms but also of mammals is important in connection with the possibilities for their efficient and safe application. That is why the subject of this article are the studies of the biological activity and possibilities for practical application of AgNPs.
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