Abstract
Present study aims to evaluate antimicrobial and antioxidant activities of the crude methanolic extract and different fractions of the Epilobium roseum (Schreb). The extract and fractions were used against pathogenic bacteria (Bacillus subtilis, Bacillus atrophaeus, Klebsiella pneumonia and Pseudomonas aeruginosa) and fungal strains (Aspergillus niger and Aspergillus flavus). The methanolic extract and their sub fraction n-hexane showed a prominent inhibition zone against all bacterial strains but inactive against fungal strains. The various extracts of Epilobium roseum (Schreb) from various parts were tested for their antioxidant activity by 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) assay. The IC50 of the stem and root of methanolic extract and their sub fraction n-hexane showed best activity ranged between 22.73 ± 6.92, 21.49 ± 6.26 and 14.94 ± 3.54, 13.92 ± 1.04 μg/ml compared to another fraction. The results support that Epilobium roseum can be used as antimicrobial and antioxidant agents. The results support the present study that Epilobium roseum (Schreb) has a potential source of natural antibacterial, antifungal and antioxidant potentials.
Highlights
Medicinal plants are widely used for therapeutic purposes; having a potential source of biological agents such as antioxidants and antimicrobial activity and their use is of greater demand nowadays [2] [3]
It has long been recognized that naturally occurring substances in higher plants have antimicrobial and antioxidant activity [25] [26]
In the present finding the extracts of crude methanolic extract and various fractions of the Epilobium roseum (Schreb) tested for antimicrobial activity against bacterial strains i.e. Bacillus atrophaeus, Bacillus subtilis, Klebsiella pneumonia, Pseudomonas aeruginosa and two fungal strains i.e. Aspergillus niger and Aspergillus flavus
Summary
Medicinal plants are widely used for therapeutic purposes; having a potential source of biological agents such as antioxidants and antimicrobial activity and their use is of greater demand nowadays [2] [3]. According to the World Health Organization (WHO) 80% of developed countries use traditional medicine that is cheaper than synthetic medicine [9] [10]. It is important that the compounds obtained from medicinal plants have antioxidant and antimicrobial potential [10] [11] [12]. Scientific investigations showed that medicinal plants are used as an alternative healthcare treatment for several types of disease in many countries for their health contributions
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