Antimicrobial Activity of Secondary Metabolites of Fungi Isolated from Leaves of Bush Mango

Abstract

Antimicrobial activity of secondary metabolites of fungi isolated from leaves of Bush mango against some selected microorganisms (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Penicillium chrysogenum and Aspergillus fumigates) was carried out in this study. Agar well diffusion method was used to study the antimicrobial activity of the secondary metabolites and each of the secondary metabolites showed antagonist activity against the test organisms; two gram positive bacteria (Staphylococcus aureus and Bacillus subtilis), two gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and two fungi (Penicillium chrysogenum and Aspergillus fumigatus). Findings from the research indicates that the studies could also pave a way for new therapeutic agents which can be used as potential drugs against the selected microorganisms or its infections.