Abstract

Antimicrobial activity of Imidazolidinyl urea (IU) is tested in M/10 phosphate buffer solutions against two strains; Escherichia coli and Pseudomonas aeruginosa. The influences of pH, gelatin and collagen hydrolysate on its activity are also tested respectively; the following results are obtained.Antimicrobial activity of Imidazolidinyl urea (IU) has a tendency to be more effective in alkaline pH range.Imidazolidinyl urea (IU) is slightly inactivated in the presence of gelatin.But its activity is more effectively decreased in collagen hydrolysate solution, especially in the case of Pseudomonas aeruginosa. In this collagen hydrolysate solution, the growth of two microbes is less inhibited in alkaline pH range than in acid one.Weak phototoxity of Imidazolidinyl urea (IU) against Escherichia coli is recognized by irradiation of 290-350nm ray.

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