Antimicrobial activity of curcuma longa and mimosa pudica: a comprehensive review

Abstract

The active ingredient in turmeric, Curcuma longa, and the traditional medicinal plant, Mimosa pudica, have both been the subject of intensive research due to their wide range of therapeutic applications. The antibacterial, anti-inflammatory, and wound-healing qualities of Mimosa pudica have long been employed, whereas curcumin is well known for its anti-inflammatory, antioxidant, and anticancer benefits. The pharmacological advantages of these two naturally occurring substances are summarized in this article, which also discusses their possible synergistic effects, modes of action, and therapeutic uses. Our goal in examining the complimentary qualities of Mimosa pudica and curcumin is to present a through analysis that bolsters their application in integrative medicine and offers ideas for further research. Curcumin is known for its powerful anti-inflammatory, antioxidant, and anticancer properties. Its therapeutic success is related to its capacity to affect numerous cellular pathways, such as inhibiting NF-KB and activating AREs. These pathways play a vital role in reducing inflammation and oxidative stress, which contribute to chronic diseases like cancer, cardiovascular disease, and neurodegeneration. Curcumin's antibacterial characteristics make it a promising medicinal agent with broad-spectrum applications. Mimosa pudica, often known as the "sensitive plant" for its quick responsiveness to physical stimuli, has a long history in traditional medicine, especially in Ayurvedic and folk treatments. It is used for wound healing,anti-inflammatory, antibacterial, and anti-ulcer properties. The pharmacological actions of Mimosa pudica are primarily due to its rich composition of bioactive compounds, including alkaloids,flavonoids, tannins, and phenolic acids.These compounds collectively contribute to the plant's ability to modulate immune responses, promote tissue regeneration, and inhibit microbial growth.Curcumin and Mimosa pudica have complimentary mechanisms that can lead to synergistic effects. Curcumin modulates intracellular signaling pathways and transcription factors, while Mimosa pudica's bioactive ingredients also interact with extracellular targets and microbial cell walls, indicating a multimodal approach to illness management.