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Abstract
Phytochemical screening of the crude extract and their fractions from the root of L. domesticum exhibited various groups of secondary metabolites. The root powder was macerated by methanol, then the crude extract was stepwise partitioned with n-hexane and chloroform. The crude extract and all fractions were phytochemically tested for alkaloids, terpenoids, flavonoids, and phenolics, and it was evaluated for antimalarial, anti-termite, and antifungal activities. The results revealed that at 5% (w/v) chloroform fraction which contained flavonoids and triterpenoids showed high antimalarial activity against Plasmodium falciparum with IC50 value 1.4 g/mL and methanol fraction at a concentration of 5% (w/v) which contained phenolics showed anti-termite and antifungal activities by 100% mortality against Coptotermes curvignathus and 100% inhibition to fungal mycelia growth of Tyromyces palustris (TYP), respectively.
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