Anti-Fungal Activities of Azadirachta indica Seed Extract against Candida Species

Abstract

At present, multidrug-resistant (MDR) fungal species have become widespread worldwide, which leads to high morbidity and mortality. As of now, only a few antifungal agents are coming up in the pharmaceutical industry. This may lead to a threat to humanity for their survival. In this study, we explored the possible antifungal action of ethanolic extract of Azadirachta indica, seeds against MDR and ATCC strains of Candida species. The extract showed antifungal activities with MIC varied between 0.76 and 1.56 mg/mL in both MDR and ATCC fungal species. Thus, Azadirachta indica ethanolic seed extract is an effective antifungal agent on MDR fungal species and may help save the lives of many critically ill patients.