Antifertility Effect of Polyaniline with Iron α-Fe2O3 on Epididymal Sperm of Mice

Abstract

Chemical polymerization produces polyaniline in two concentrations (0.02,0.05g) at room temperature. The reaction of polymerization was exothermal in nature. The characterization peak was observed in the FTIR range between 1470 and 1560cm-1which defined benzenoid and quinoid ring. To find out the effects Fe2O3, this investigation was carried out with two weights of Fe2O3 (0.05 and 0.02 g). In the experiment part, 32 mice were separated into eight groups, as indicated. The experiment lasted for 35 days. The results showed a significant (P < 0.05) decrease in sperm motility, concentration, percentage of live sperm and testosterone concentration with a significant (P < 0.05) increase in the percentage of abnormal sperm in group treated with PANI-Fe2O3-Cys without magnetic field in comparison with control group. The results also showed a significant (P < 0.05) increase in sperm motility, Relative sperm count of live sperm and testosterone concentration, with a significant (P < 0.05) decrease in the percentage of abnormal sperm in group treated with PANI-Cys and PANI-Fe2O3-Cys exposed to magnetic field in comparison with the samples without magnetic field. The group treated with PANI alone showed an improvement in all parameters studied except the percentage of abnormal sperms which showed a significant (P < 0.05) decrease. Using the alternating magnetic field, it was found that it has a obvious effect on the work of the material PANI- Fe2O3-Cys and PAN-Cys. Thus, it affects sperm motility