Abstract

Anticoagulant rodenticides (AR) are among the most commonlyused rodent control pesticides. The current second-generationrodenticides in worldwide use are referred to as superwarfarins.These substances have relatively low toxicity to humans but significanttoxicity to animals, including pets.AR work at the level of hepatocytes by blocking the synthesisof plasma coagulation factors II, VII, IX, and X as well as proteinsC, S, and Z, resulting in severe coagulation disorders predominantin the clinical picture.Deaths associated with AR poisoning are the result of haemorrhagesinto the gastrointestinal tract, peritoneal cavity, or intracranialcavities.Medico-legal diagnosis of AR poisonings is based on the clinicalpicture, autopsy, and histopathological and toxicological examinations.

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