Anticancer Potential of Calotropis procera: An Overview

Abstract

Medicinal plants have incredible importance because of the presence of many types of components present in it, and they become the source for the synthesis of active pharmaceutical ingredients (API). Calotropis procera is a xerophytic shrub, with soft, tall; numerous shrubs with small flowering branches or small trees belonging to the family of Asclepiadaceae, distributed globally over the tropical and subtropical region of Asia and Africa. It is well known in traditional medicine to have cleansing and anti-ageing properties as well as used in the mitigation of various ailments as antiulcer, anti-leprotic, cytotoxic, anti-emetic, anti-coagulant and anticancer activities. It contains various chemical constituents like cardiac glycoside, triterpens, flavanoids, steroids and other phenolic components in various parts of plant was well known for its diverse pharmacological and biological activities. Different extracts of plant and parts of plants possess significant in-vitro and in-vivo cytotoxic, anti-tumour and anti-proliferative activity in various cell lines and tumor cells which indicate the considerable potential of Calotropis procera for anticancer adjutants. The objective of the presentr eview is to provide systematic information about the phytochemical and various extracts of Calotropis procera as potential candidate for cancer treatment.Â