Abstract
Staphylococcus spp. have become important human pathogens in recent decades due to the selection of resistant bacteria and the spread of their resistance genes in the environment. This study aimed to evaluate the resistance of Staphylococcus spp. obtained from sewage in the city of Manaus, Amazonas state, Brazil. The isolates were tested for susceptibility to antimicrobials using the Kirby-Bauer method for ampicillin, azithromycin, ciprofloxacin, clindamycin, chloramphenicol, erythromycin, gentamicin, oxacillin, cefoxitin, linezolid, penicillin, rifampicin, sulfazotrim, tetracycline and vancomycin. Among the strains isolated from sewage, the greatest resistance was observed for penicillin and oxacillin, with 100% of isolates resistant to these antibiotics. Some antibiotics had resistant and sensitive strains (ampicillin, clindamycin, erythromycin, cefoxitin, azithromycin). Staphylococcus spp. were identified as sensitive to ciprofloxacin chloramphenicol gentamicin linezolid sulfazotrim tetracycline, vancomycin, with no strain resistant to these antibiotics.
Highlights
Staphylococcus aureus is one of the main human pathogens, which can trigger a variety of infectious diseases, such as skin and soft tissue infections, endocarditis, osteomyelitis, bacteremia and lethal pneumonia
The ability of bacteria to develop and acquire antimicrobial resistance has quickly led to the emergence of multidrug-resistant strains, such as methicillin-resistant S. aureus (MRSA)
The highest resistance was observed for penicillin and oxacillin, with 100% of isolates resistant to these antibiotics
Summary
Staphylococcus aureus is one of the main human pathogens, which can trigger a variety of infectious diseases, such as skin and soft tissue infections, endocarditis, osteomyelitis, bacteremia and lethal pneumonia. Due to the adaptation of bacteria and the use of large amounts of antibiotics, resistant S. aureus strains have been selected. The ability of bacteria to develop and acquire antimicrobial resistance has quickly led to the emergence of multidrug-resistant strains, such as methicillin-resistant S. aureus (MRSA). These strains have become endemic in most hospitals worldwide. The frequent use of antibiotics has contributed to the spread of resistant bacteria or their resistance genes in the environment. There is a need to monitor Staphylococcus resistance, as well as the appropriate use of antibiotics, to minimize the prevalence of antimicrobial resistance
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
