Abstract
In this report, nanosized ZnO NPs (NPs stands for nanoparticles) have been prepared via a simple biosynthesis route with the fruit extract of Azadirachta indica (neem tree) for antibacterial study and labelled as F1. The fruit extract of Azadirachta indica has different phyto-molecules which are used as coating and stabilizing agents. This as-synthesized F1 has been analyzed using several advanced techniques like Fourier transform infrared (FT-IR), transmission electron microscopy (TEM), UV–visible spectroscopy, and powder X-ray diffraction (PXRD). UV–Visible spectrum has revealed that the maximum absorbance value was obtained at 367.53 nm and bandgap energy has been determined at 2.6530 eV from the tauc’s plot. The hexagonal wurtzite crystalline structure has been displayed by the PXRD pattern. The shape and size of biosynthesized ZnO NPs have been examined with TEM micrographs. These ZnO NPs (F1) are obtained rough sheet-shaped where the thickness of sheet has been found approximately 20–25 nm and length 200–250 nm respectively. The investigation on antibacterial activity has been accomplished using as-prepared F1 with the help of the broth dilution method. These F1 exhibit antimicrobial activity against utilized bacteria namely Escherichia coli, Streptococcus pneumonia, and Staphylococcus aureus. The MIC values have been found at 140 μg/mL, 120 μg/mL, and 135 μg/mL for Escherichia coli, Streptococcus pneumoniae, and Staphylococcus aureus respectively (MIC stands for minimum inhibitory concentrations).
Published Version
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