Antibacterial Potency Screening of the Crude Extracts of Adenanthera pavonina L.

Abdul Matin W Islam,O Ali Mandal

doi:10.13189/ujmr.2015.030302

Abstract

The anitbacterial potency screening of the crude extracts of leaves, seed and stem wood of Adenanthera pavonina L. were tasted against 15 Gram-positive and Gram-negative bacteria along with a standard antibiotic, Ciprofloxacin. The in vitro screening for antimicrobial potency was carried out by following the agar diffusion and micro broth dilution techniques. Among the fifteen bacterial strains tested the chloroform fraction of the seed extract showed promising antibacterial efficacy against Salmonella-β-haemolyticus, Serratia dysenteriae and Escherarichia coli. The susceptibility order of extracts were seed>leaf>stem. The MIC values of the chloroform seed extract were determined 256µg/ml againstB. cerus; 128 µg/ml against S.-β-haemolyticus, S. dysenteriaeand 64 µg/ml against Klebsiella sp. The MIC values of the chloroform extracts of stem wood were128µg/ml S.-β-haemolyticus; 64 µg/ml against B. megaterium, S. sonnei and 32 µg/mlagainst S. typhi.

Highlights

The plants are the natural chemical factories that synthesize unmemorable compounds
The anitbacterial activity of A. pavonina extractives collected in petroleum ether, acetone, chloroform and methanol of leaves, seed and stem wood were tested against 15 bacteria
A correlation was found between the antibacterial activity observed by agar disc diffusion assay and Minimum Inhibitory Concentration (MIC) determination

Summary

Introduction

The plants are the natural chemical factories that synthesize unmemorable compounds. The plants-derived compounds have been utilized by the human kind from time immemorial in different sectors of life, including public health and pest management. Adenanthera Pavonina, Extract, Antibacterial Screening, Disc Diffusion Assay, Zone of We report a comparative potency of extracts obtained in different solvents from leaves, seed and stem wood of A. pavonina to inhibit Gram-positive and Gram-negative bacteria due to their random use in customary and traditional medicine to cure common ailments such as rheumatism, diarrhea, chronic ophthalmia etc.

Results

Conclusion