Abstract
A composite resin containing surface pre-reacted glass ionomer(S-PRG) has become widely used as filler or other dental materials in dental treatment. In this mini-review, we briefly summarizethe antibacterial activities of S-PRG on different oral bacteria. The inhibitory effect of S-PRG on plaque formation in the oral cavity has been observed. Streptococcus mutans adherence has been shown to be inhibited by S-PRG. S-PRG is also considered to be effective in caries prevention because S-PRG eluate could inhibit biofilm formation and disrupt salivary mature polymicrobial biofilm. S-PRG eluate has suppressed the protease and gelatinase activities of Porphyromonas gingivalis, which is one of the most important periodontopathic bacteria. Coaggregation by P. gingivali sand Fusobacterium nucleatum was also inhibited by S-PRG eluate. Other work has shown that an endodontic sealer containing S-PRGhad an antibacterial effect on some endodontic bacteria. Oral rinsing with S-PRG eluate was also effective in reducing oral malodor production. In this way, S-PRG has antibacterial effect, and it will be further applied for various dental materials and contribute to preventing oral diseases.
Highlights
Dental caries and periodontitis are two major causes of tooth loss in adults
Glass ionomer cement (GIC) is known to have an ion exchange and fluoride release activity, which results in interfering with cariogenic bacteria and remineralization [1,2,3,4,5]
Bacterial adherence is the first step in caries initiation, and S-PRG-containing materials are considered to be less susceptible to cariogenic bacteria
Summary
Dental caries and periodontitis are two major causes of tooth loss in adults. To reduce dental caries, it is necessary to prevent demineralization of the intact tooth surface and to promote remineralization of early stage tooth decay. Secondary caries, which is caries lesion developed adjacent to restorations, is the problem and is the main cause for the replacement of restorative materials. To overcome these problems, much research on dental materials has been performed. A composite resin containing prereacted glass ionomer(S-PRG) filler has become widely used in dental treatment [7]. S-PRG is known to release several types of ions, including Al, B, Na, Si, Srand F [12]. The effects of S-PRG filler and its released ions on hard tissue were extensively investigated, including the anti-demineralization and re-mineralization activity.
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