Abstract
The present study was undertaken to determine the antibacterial effect of short-chain fatty acids (SCFA) such as acetic, propionic and butyric acids on gnotobiotic Artemia franciscana nauplii against Vibrio parahaemolyticus. An initial experiment was undertaken to determine the antibacterial effect of different concentrations (1, 10 and 100 mM) of individual SCFA against V. parahaemolyticus through bacterial growth study at pH 6. In this study, the pathogen growth was completely inhibited at 100 mM concentration of all the tested SCFA. In another investigation, the different pH (5–7) on growth inhibitory effect of 20 mM SCFA was tested against V. parahaemolyticus through bacterial growth study. In this study, the pathogen growth was highly inhibited at pH 5 in all the tested SCFA. The Artemia nauplii were gnotobiotically reared in 20 mM SCFA supplemented medium and the mortality was recorded at an every 6 h interval up to 60 h after challenged with V. parahaemolyticus. The reduction in mortality (%) of A. franciscana nauplii over control was ranged from 25.36% to 38.56% in all the tested SCFA.
Published Version
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