Antibacterial Effect of Different Concentrations of Zinc Sulfate on Multidrug Resistant Pathogenic Bacteria

Abstract

Background: The most important reason for the appearance and distribution of strains of bacteria with multi-drug resistant is the overuse of antibiotics which lead to search for agents that might have antibacterial properties. Objective: The present study designed to investigate the growth inhibitory effect of different concentrations of zinc sulfate against multidrug resistant Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Proteus spp., Klebsiella spp., Pseudomonas aeruginosa and Enterobacter spp. Method: The agar well diffusion technique was used to establish the antibacterial action of zinc sulfate by measuring the zone of inhibition diameter. Results: All concentrations of zinc sulfate showed antibacterial effect. The maximum antibacterial effect of zinc sulfate had shown with (10mg/ml) concentration for Staph.aureus , Staph.epidermidis and klebsiella whereas the maximum antibacterial effect of zinc sulfate had shown with (14mg/ml ) concentration for E.coli, Enterobacter, proteus and pseudomonas. Conclusion: Different concentrations of zinc sulfate were found to have antibacterial effect against multidrug resistant Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Proteus spp., Klebsiella spp., Pseudomonas aeruginosa and Enterobacter spp.