Abstract

With the development of new technology industry, nanoparticle is more and more getting valued as one of the most promising technologies in the technological revolution in the 21st century. In recent years, nanotechnology applied in biomedicine is in the ascendant and among the most metal nanoparticles, the silver nanoparticle(AgNP) is s kind of the most common nanomaterials used in wound healing according to its antibacterial properties. For the consideration of biocompatibility and dispersion of the AgNPs, nanocomposites that AgNPs combined with other natural materials like lignin, chitosan, nanofiber and cellulose have been researched a lot to apply to synthesize the wound healing materials. However, there is no sufficient evidence to prove the mechanism of the AgNPs’ toxicology until now. Nowadays, AgNPs have been widely used in products, as a result, how to correctly explain the toxicity of AgNPs and the safety to human body and the environment is urgent. In this article, the use of AgNPs combined with other natural materials is reviewed. Furthermore, the possible toxicology which is not mentioned before and the possible solutions are proposed.

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