Abstract
Abstract Cavities, commonly caused by bacteria metabolic acid in dental plaque, pose a prevalent dental problem. This study investigates the use of biocompatible zeolitic imidazolate framework 67 (ZIF-67) for cavities. ZIF-67 exhibits strong metal-binding properties and a large surface area. Streptococcus mutans (S. mutans) are responsible for dental plaque and cavities. In vitro studies have demonstrated that ZIF-67 could effectively inhibit S. mutans. Experimental evidence reveals that ZIF-67 can disrupt pathogen cell walls, resulting in leakage of DNA and RNA. Additionally, ZIF-67 inhibits biofilm formation on tooth surfaces without cytotoxicity on mammalian gingival fibroblast cells. These findings demonstrate the promising potential of ZIF-67 in preventing cavities and their biomedical applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
