Abstract
Snake venoms are composed of active substances that present a diversity of biological effects such as neurotoxicity, myotoxicity, antiparasitic and antibacterial activities. This study was undertaken to evaluate the antimicrobial activity on Gram-negative and Gram-positive bacteria of the venom from Philodryas nattereri. This activity was investigated against Escherichia coli (ATCC 10536), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 9027), and Salmonella choleraesuis spp. choleraesuis (ATCC 10708) using a broth microdilution method. Philodryas nattereri venom significantly inhibited the growth of Staphylococcus aureus, Salmonella choleraesuis spp. choleraesuis and, to a lesser extent, Pseudomonas aeruginosa, but was inactive against Escherichia coli. These results indicate the potential of P. nattereri venom as a source of antibacterial compounds.
Published Version
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