Abstract
ObjectiveTo test efficacy of Parmelia perlata (P. perlata), which is used in traditional medicine for rapid wound healing against test bacteria that cause wound infections. MethodsDifferent solvents such as methanol, ethyl acetate and acetone were used for extraction of P. perlata. The sensitivity of the test bacteria to solvent extracts of P. perlata was tested by measuring the zone of inhibition on growth media and by determining the minimal inhibitory concentration and minimal bactericidal concentration. ResultsMethanol, ethyl acetate and acetone extracts of P. perlata have shown inhibitory activity against Staphylococcus aureus (S. aureus). ConclusionsThe results of the present study indicate that P. perlata has potential antibacterial compounds against S. aureus that causes multitude of skin infections among human beings. Development of drugs from natural compounds can help us to combat antibiotic–resistant bacteria.
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