Abstract
Background: Probiotics have antibacterial effects against pathogenic bacteria in the gut while maintaining the balance of intestinal flora. This study aimed to experiment the antibacterial activity of two Lactobacillus species against pathogenic bacteria. Methods: Two different species of Lactobacillus lactiplantibacillus plantarum (CIP 103151) and Limosilactobacillus fermentum (CIP 102980) that were previously isolated from fermented Etsako Osuemegbe rice were investigated for their inhibitory ability against three (3) organisms (Escherichia coli, Staphylococcus aureus and Salmonella). Agar overlay method was employed and plates were examined for clear zone of inhibition. Results: The lactiplantibacillus plantarum inhibited the growth of E. coli, S. aureus, and Salmonella sp with diameter zone of inhibition range between 15.00+0.57 and 18.00+0.77 mm, while Limosilactobacillus fermentum inhibited the growth of E. coli, S. aureus, and Salmonella sp with diameter zone of inhibition range between 14.00+1.00 and 18.00+0.50 mm. Conclusion: The findings in this study suggest that LAB species can be used as alternate antibiotic if explored due to their ability to inhibit the growth of pathogenic organisms.
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