Abstract
Present study is conducted to analy se the antibacterial activity of flower heads of W edelia trilobata against pathogenic bacterial strains and to analyse phytochemical background of various extracts. Fresh flower heads collected from Kerala, India. Air dried flower heads were extracted succ essively in petroleum ether, chloroform, acetone, ethanol and water. Preliminary antibacterial activity was an alysed by disc - diffusion method and further confirmed by MIC and MBC. Prelim inary detection of phytochemical s was done. Among the ten bacterial s trains nine showed considerable inhibition of growth towards acetone extract. Acetone extract selected for detailed antibacterial evaluation tests like minim um inhibitory concentration (MIC) and minimum bacterial concentration (MBC). The MIC and MBC of flo ral extracts tested against one of the most sensitive strains, Streptococcus haemolyticus . MIC and MBC values were 25 mg/ml and 50 mg/ml respectively. Preliminary phytochemical evaluation reve aled the presence of flavonoids, phenolics and terpenoids in act ive acetone extract. The present investigation showed the effectiveness of crude extract of this plant against tested bacterial strains. The presence of potential phytochemicals like phenolics, flavonoids and terpenoids in active acetone extract might be o ne of the reasons for its antibacterial property.
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