Abstract
Fronds (leaves) of Lindsaea ensifolia Sw., belonging to pteridophyte family: Lindsaeaceae, has been evaluated for its antibacterial potential and phytochemical contents in various solvent extracts of increasing polarity against certain pathogenic bacteria involved in human skin diseases. Antibacterial activity was tested by disc diffusion method. Petroleum ether, acetone, methanol and water extracts of Lindsaea ensifolia has been tested for its antibacterial activity. Maximum antibacterial activity was shown by acetone and methanol extract as compared to others. Antibacterial activity was confirmed by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). MIC and MBC values of acetone extract of 12.5mg/ml and 25mg/ml were observed towards Micrococcus luteus MIC and MBC values of 25mg/ml and 50mg/ml were observed towards Staphylococcus aureus and Pseudomonas aeruginosa. Flavonoids, phenols, terpenes were detected in active acetone extract. The study proves that Lindsaea ensifolia's antibacterial principles, can hinder the growth and multiplication of some multidrug resistant bacterial strains.
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