Abstract
Kesambi plant ( Schleichera oleosa ) is a medicinal plant belongs to family Sapindaceae , commonly found in tropical and subtropical regions of the world. In Indonesia, kesambi plants can be found in Java and Bali island. The purpose of this study is to extraction and antibacterial activity test of steam bark extract of kesambi against Escherichia coli and Staphylococcus aureus . Extraction was done by maceration method using n -hexane, ethyl acetate and methanol. Antibacerial test using Kirby bauer method by measure inhibition zone. Phytochemical screening shown that n -hexane extract contain triterpenes and steroid compounds. Ethyl acetate extract contain triterpenes, flavonoid, steroid, and fenolic compounds. Methanol extract contain flavonoid, fenolic and triterpenes compounds. Inhibition zone of n -hexane, ethyl acetate and methanol extracts against E. coli and S. aureus at concentration of 5000 µg/mL showed 4.4; 7.9; 4.6 mm and 4.7; 8.9; 4.5 respectively, while amoxicillin and ciprofloxacin as positive control at concentration of 100 µg/mL showed 6.9 and 7.1 mm respectively. Kesambi extract have potential as antibacterial against E. coli and S. aureus . Keywords: Kesambi; antibacterial; Eschericia coli ; Staphylococus aureus
Highlights
Infectious disease and parasites are one of the major diseases in the world
In Indonesia, infection deseases is one of the major caused of death for children and still a big health problem in all levels of society (Singh & Pandeya, 2011)
Infectious disease of the skin tissue that commonly affects the public caused by various bacteria (Mustaffa et al 2011)
Summary
Infectious disease and parasites are one of the major diseases in the world. According to World Health Organization (WHO) data in 2011, infectious and paracites diseases are the third leading cause of death in the world. In Indonesia, infection deseases is one of the major caused of death for children and still a big health problem in all levels of society (Singh & Pandeya, 2011). Infectious disease of the skin tissue that commonly affects the public caused by various bacteria (Mustaffa et al 2011). Bacteria cause the most common skin disease and infection is Staphylococcus aureus and Escherichia coli. One of the palnt that have potential to treat various deseases is Kesambi. Kesambi is one of plants that have the potential to treat various deasease.
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