Abstract
Anti-Ulcerogenic Effect of Unripe Plantain (Musa paradisiaca) Pulp on Indomethacin-Induced Ulcer in Wistar Rat
Highlights
The proportion of the human population with ulcer has recorded a geometric up-shoot recently, especially in Nigeria.[1]
These bioactive components may have acted synergistically to achieve the anti-ulcerogenic activities of Musa paradisiaca pulp.[22,23,24,25,26]
Percentage ulcer inhibition revealed that the fruit pulp at a dose of 400 mg/kg (51.83%) inhibited indomethacin-induced ulcer more than cimetidine (49.54%)
Summary
The proportion of the human population with ulcer has recorded a geometric up-shoot recently, especially in Nigeria.[1]. Medicinal plants have been helpful in the management of human diseases as reported by various research findings. The use of Musa paradisiaca (plantain) in the treatment of human diseases has been reported in various parts of the world.[8] The pharmacological activities of the fruits, stem juice and flowers of Musa paradisiaca have been documented by various researchers.[9,10,11,12] various studies have been conducted with different parts of the plant, the pharmacological properties of the unripe fruit pulp remains unexploited.[13] Moreso, there is a claim about the traditional use of the unripe fruit pulp in the management of ulcer. The study evaluated the anti-ulcer properties of unripe plantain fruit pulp
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