Abstract
Nowadays, people are busier and busier for working and living, and suffer a lot of pressure on their body or mind. Therefore, people are prone to have fatigue activity and decrease their working efficiency and happiness. It was reported that fatigue is a common symptom in the community, with up to half of the general population complaining of fatigue. More and more researchers devoted themselves to studying natural active ingredients in organism as the anti-fatigue drugs to release fatigue symptom. However, these natural ingredients were difficult to obtain from plants, animals and microorganisms by separating and purifying. In addition, some active substances have many side effects. In our study, we employed tea seed oil as main ingredients blended with bis-(carboxyethylgermanium) sesquioxide (Ge-132) to investigate the effects of anti-fatigue on mice by administrating mice with low dose, intermediate dose and high dose of tea seed oil complex for 0, 2 or 4 weeks. The specific tests of studying effects of anti-fatigue were body weight, weight-loaded force swimming, blood urea nitrogen, blood lactic acid and hepaticglycogen. And the results showed that appropriate level of tea seed oil complex could decrease the body weight and prolong the weight-loaded swimming time, and had an active effect on the bloodurea nitrogen, hepatic glycogen and blood lactic acid level mice, which significantly embodied the anti-fatigue activity of tea seed oil complex.
Highlights
Fatigue is a common symptom in the community, with up to half of the general population complaining of fatigue in most surveys [1] [2]
Our goal is to evaluate the effect of anti-fatigue activity of the complex of tea seed oil blended GE-132 in mice
The intermediate dose group and high dose group showed a significant increase in swimming time to exhaustion compared to the control group after administrating with tea seed oil complex for 4 weeks
Summary
Fatigue is a common symptom in the community, with up to half of the general population complaining of fatigue in most surveys [1] [2]. (2015) Anti-Fatigue Effect of Blended Camellia oleifera Abel Tea Oil and Ge-132 in Mice. In the past few decades, health scholar and athletic physiologist have been looking for natural active ingredients to release the fatigue and accelerate the elimination of fatigue in human beings [8]. These natural ingredients are difficult to obtain from plants, animals and microorganisms by separating and purifying. Some active substances have many side effects and are more expensive for daily use
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