Abstract
To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements.
Highlights
Otitis media with effusion (OME) is a chronic inflammatory disease that causes partial deafness
OME is a common disease in children and the only effective treatment is surgical drainage of the middle ear with insertion of a tympanostomy tube in the tympanic membrane done under general anaesthetic [2]
The severity of the inflammation is assessed via the blood content of tissue, simulated by polyester resin based mucosa phantoms and human hands exposed to cold, and measured by the in this paper defined inflammation index
Summary
Otitis media with effusion (OME) is a chronic inflammatory disease that causes partial deafness. The viscosity of the effusion, caused by the mucin content, is too high to allow natural drainage of the middle ear via the Eustachian tube [1]. OME is a common disease in children and the only effective treatment is surgical drainage of the middle ear with insertion of a tympanostomy tube in the tympanic membrane done under general anaesthetic [2]. There is no clinically available method of measuring the inflammatory state of the middle ear mucosa. If there were, this would give clinicians a rational method of determining which patients need to be followed up and those which could be discharged from the clinic
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